FXR2 antibody (Middle Region)

Catalog No. ABIN2778916

Cited in 1 publication. The Rabbit Polyclonal anti-FXR2 antibody (ABIN2778916) specifically detects FXR2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig samples.

Quick Overview for FXR2 antibody (Middle Region) (ABIN2778916)

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FXR2 Antibody

Binding Specificity: Middle Region

Purpose: FXR2 Antibody - middle region

Sequence: RGRRTGGPAY GPSSDVSTAS ETESEKREEP NRAGPGDRDP PTRGEESRRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FXR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FXR2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40557-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FXR2 antibody (ABIN2778916)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for FXR2

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Alternative Name: FXR2

Background:

Background Information: FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Fragile X mental retardation, autosomal homolog 2

Alternative Symbols: FXR2P, FMR1L2

Protein Name: Fragile X mental retardation syndrome-related protein 2

Molecular Weight: 74kDa

Gene ID: 9513

NCBI Accession: NP_004851

UniProt: P51116