FXR2 antibody (Middle Region)

Catalog No. ABIN2778916

Product Details anti-FXR2 Antibody

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGRRTGGPAY GPSSDVSTAS ETESEKREEP NRAGPGDRDP PTRGEESRRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FXR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FXR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 673 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FXR2 antibody (ABIN2778916)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for FXR2

Target: FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

Alternative Name: FXR2 (FXR2 Products)

Synonyms: id:ibd5046 antibody, zgc:56215 antibody, zgc:77472 antibody, FMR1L2 antibody, FXR2P antibody, Fxr2h antibody, FMR1 autosomal homolog 2 antibody, fragile X mental retardation, autosomal homolog 2 antibody, FXR2 antibody, fxr2 antibody, Fxr2 antibody

Background: FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FMR1L2, FXR2P
Protein Interaction Partner: MORF4L1, FMR1, MRPL43, PRAM1, CEP44, HMBOX1, C1orf35, NIF3L1, TBC1D22B, CEP55, FAM90A1, PAF1, LASP1, POM121, FXR2, ZBTB22, AP1M1, SCEL, YES1, SRPK2, PIM1, PCBD1, MFAP1, LCP2, CDKL3, BAZ2B, CAMK2D, BYSL, C10orf62, MIA3, ZMAT2, SYT6, SYTL4, NDN, KIF1A, UBC,
Protein Size: 673

Molecular Weight: 74 kDa

Gene ID: 9513

NCBI Accession: NM_004860, NP_004851

UniProt: P51116