RBM8A antibody (N-Term)

Catalog No. ABIN2778929

Product Details anti-RBM8A Antibody

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LHEAGGEDFA MDEDGDESIH KLKEKAKKRK GRGFGSEEGS RARMREDYDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RBM8A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 174 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Alternative Name: RBM8A (RBM8A Products)

Synonyms: BOV-1A antibody, BOV-1B antibody, BOV-1C antibody, C1DELq21.1 antibody, DEL1q21.1 antibody, MDS014 antibody, RBM8 antibody, RBM8B antibody, TAR antibody, Y14 antibody, ZNRP antibody, ZRNP1 antibody, 2310057C03Rik antibody, AA673428 antibody, Rbm8 antibody, RBM8A antibody, rbm8 antibody, rbm8a antibody, rnp-5 antibody, fb34f03 antibody, wu:fb34f03 antibody, zgc:110525 antibody, rbm8-A antibody, rbm8a-A antibody, rbm8-B antibody, RNA binding motif protein 8A antibody, RNA binding motif protein 8a antibody, RNA binding motif protein 8A S homeolog antibody, RNA binding motif protein 8A L homeolog antibody, RBM8A antibody, Rbm8a antibody, rbm8a antibody, rbm8a.S antibody, rbm8a.L antibody

Background: RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
Alias Symbols: Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014
Protein Interaction Partner: MAGOHB, MAGOH, UBC, SUZ12, RNF2, PARK2, SRPK2, SRPK1, FBXO25, tat, UPF3B, SMG9, SMG8, PABPC1, UPF2, SMG5, SMG1, RUVBL2, RBM8A, SMG7, EIF4A3, TTI1, RUVBL1, UPF1, NCBP2, TOE1, SF3B2, RPS16, RPL11, HBB, GSPT1, ZFP36L1, UNC119B, SLIRP, LSM2, CIAPIN1, TFCP2L1,
Protein Size: 174

Molecular Weight: 19 kDa

Gene ID: 9939

NCBI Accession: NM_005105, NP_005096

UniProt: Q9Y5S9