RBM8A antibody (N-Term)

Catalog No. ABIN2778929

The Rabbit Polyclonal anti-RBM8A antibody is suitable to detect RBM8A in samples from Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for RBM8A antibody (N-Term) (ABIN2778929)

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RBM8A Antibody

Binding Specificity: N-Term

Purpose: RBM8A Antibody - N-terminal region

Sequence: LHEAGGEDFA MDEDGDESIH KLKEKAKKRK GRGFGSEEGS RARMREDYDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RBM8A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110954

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Alternative Name: RBM8A

Background:

Background Information: RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

Gene Name: RNA binding motif protein 8A

Alternative Symbols: TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1

Protein Name: RNA-binding protein 8A

Molecular Weight: 19kDa

Gene ID: 9939

NCBI Accession: NP_005096

UniProt: Q9Y5S9