BCAS2 antibody (Middle Region)

Catalog No. ABIN2778956

Cited in 1 publication. The Rabbit Polyclonal anti-BCAS2 antibody (ABIN2778956) specifically detects BCAS2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse samples.

Quick Overview for BCAS2 antibody (Middle Region) (ABIN2778956)

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCAS2 Antibody

Binding Specificity: Middle Region

Purpose: BCAS2 Antibody - middle region

Sequence: SKLREMESNW VSLVSKNYEI ERTIVQLENE IYQIKQQHGE ANKENIRQDF

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BCAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCAS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40613-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BCAS2 antibody (ABIN2778956)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for BCAS2

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Alternative Name: BCAS2

Background:

Background Information: BCAS2 belongs to the SPF27 family. It is involved in mRNA splicing. The protein might play an important role in breast cancer development by increasing the estrogen receptor's function.

Gene Name: Breast carcinoma amplified sequence 2

Alternative Symbols: DAM1, SPF27, Snt309

Protein Name: Pre-mRNA-splicing factor SPF27

Molecular Weight: 26kDa

Gene ID: 10286

NCBI Accession: NP_005863

UniProt: O75934