SRSF10 antibody (N-Term)

Catalog No. ABIN2779003

This Rabbit Polyclonal antibody specifically detects SRSF10 in WB. It exhibits reactivity toward Human, Mouse, Guinea Pig, Rat, Rabbit, Dog and Cow.

Quick Overview for SRSF10 antibody (N-Term) (ABIN2779003)

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Reactivity: Human, Mouse, Guinea Pig, Rat, Rabbit, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRSF10 Antibody

Binding Specificity: N-Term

Purpose: SRSF10 Antibody - N-terminal region

Sequence: MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUSIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUSIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40671-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Alternative Name: SRSF10

Background:

Background Information: This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.

Gene Name: serine and arginine rich splicing factor 10

Alternative Symbols: NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149

Protein Name: serine/arginine-rich splicing factor 10

Molecular Weight: 31kDa

Gene ID: 10772

NCBI Accession: NP_473357

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization