CNOT6 antibody (N-Term)

Catalog No. ABIN2779084

The Rabbit Polyclonal anti-CNOT6 antibody is suitable to detect CNOT6 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for CNOT6 antibody (N-Term) (ABIN2779084)

Target: CNOT6 (CCR4-NOT Transcription Complex, Subunit 6 (CNOT6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNOT6 Antibody

Binding Specificity: N-Term

Purpose: CNOT6 Antibody - N-terminal region

Sequence: EISGKVRSLS ASLWSLTHLT ALHLSDNSLS RIPSDIAKLH NLVYLDLSSN

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CNOT6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40812-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT6

Target: CNOT6 (CCR4-NOT Transcription Complex, Subunit 6 (CNOT6))

Alternative Name: CNOT6

Background:

Targeted Subunit: 6

Background Information: CNOT6 is a subunit of the CCR4-NOT core transcriptional regulation complex. CNOT6 has a 3'-5' RNase activity and prefers polyadenylated substates.The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.

Gene Name: CCR4-NOT transcription complex, subunit 6

Alternative Symbols: CCR4, Ccr4a

Protein Name: CCR4-NOT transcription complex subunit 6

Molecular Weight: 63kDa

Gene ID: 57472

NCBI Accession: NP_056270

UniProt: Q9ULM6