CNOT6 antibody (N-Term)

Catalog No. ABIN2779084

Product Details anti-CNOT6 Antibody

Target: CNOT6 (CCR4-NOT Transcription Complex, Subunit 6 (CNOT6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EISGKVRSLS ASLWSLTHLT ALHLSDNSLS RIPSDIAKLH NLVYLDLSSN

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CNOT6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 557 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT6

Target: CNOT6 (CCR4-NOT Transcription Complex, Subunit 6 (CNOT6))

Alternative Name: CNOT6 (CNOT6 Products)

Synonyms: CCR4 antibody, A230103N10Rik antibody, AA407540 antibody, AW456442 antibody, RGD1310783 antibody, wu:fa03c11 antibody, wu:fc17f01 antibody, zgc:65822 antibody, CCR4-NOT transcription complex subunit 6 antibody, CCR4-NOT transcription complex, subunit 6 antibody, CCR4-NOT transcription complex, subunit 6a antibody, CNOT6 antibody, Cnot6 antibody, cnot6a antibody, cnot6 antibody

Background: CNOT6 is a subunit of the CCR4-NOT core transcriptional regulation complex. CNOT6 has a 3'-5' RNase activity and prefers polyadenylated substates.The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.
Alias Symbols: CCR4, KIAA1194
Protein Interaction Partner: TNKS1BP1, CNOT7, CNOT10, CNOT1, CHAF1A, RQCD1, CNOT3, CNOT2, HSP90AA1, UBC, PABPC1, ELAVL1, CNOT6, CNOT8,
Protein Size: 557

Molecular Weight: 63 kDa

Gene ID: 57472

NCBI Accession: NM_015455, NP_056270

UniProt: Q9ULM6