HSD17B11 antibody (Middle Region)

Catalog No. ABIN2779101

This Rabbit Polyclonal antibody specifically detects HSD17B11 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Horse, Rabbit and Pig.

Quick Overview for HSD17B11 antibody (Middle Region) (ABIN2779101)

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSD17B11 Antibody

Binding Specificity: Middle Region

Sequence: IYSAAKKVKE EVGDVSILVN NAGVVYTADL FATQDPQIEK TFEVNVLAHF

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Hsd17b11. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSD17B11

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Alternative Name: Hsd17b11

Background: Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
Alias Symbols: Dhrs8, Pan1b, SDR2, retSDR2
Protein Interaction Partner: Eed,
Protein Size: 298

Molecular Weight: 33 kDa

Gene ID: 114664

NCBI Accession: NM_053262, NP_444492

UniProt: Q9EQ06