HSD17B11 antibody (N-Term)

Catalog No. ABIN2779102

This Rabbit Polyclonal antibody specifically detects HSD17B11 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Monkey and Guinea Pig.

Quick Overview for HSD17B11 antibody (N-Term) (ABIN2779102)

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Monkey, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HSD17B11 Antibody

Binding Specificity: N-Term

Purpose: HSD17B11 Antibody - N-terminal region

Sequence: TGEIVLITGA GHGIGRLTAY EFAKLKSKLV LWDINKHGLE ETAAKCKGLG

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against HSD17B11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40843-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSD17B11

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Alternative Name: HSD17B11

Background:

Background Information: Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).

Gene Name: Hydroxysteroid (17-beta) dehydrogenase 11

Alternative Symbols: DHRS8, PAN1B, RETSDR2, SDR16C2, 17BHSD11, 17-BETA-HSD11, 17-BETA-HSDXI

Protein Name: Estradiol 17-beta-dehydrogenase 11

Molecular Weight: 33kDa

Gene ID: 51170

NCBI Accession: NP_057329

UniProt: Q8NBQ5