LARP7 antibody (C-Term)

Catalog No. ABIN2779104

This anti-LARP7 antibody is a Rabbit Polyclonal antibody detecting LARP7 in WB. Suitable for Human, Mouse, Rat, Dog, Horse, Pig, Cow, Guinea Pig and Rabbit. This Primary Antibody has been cited in 2+ publications.

Quick Overview for LARP7 antibody (C-Term) (ABIN2779104)

Target: LARP7 (La Ribonucleoprotein Domain Family, Member 7 (LARP7))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARP7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LARP7 Antibody

Binding Specificity: C-Term

Sequence: WQKILVDRQA KLNQPREKKR GTEKLITKAE KIRLAKTQQA SKHIRFSEYD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LARP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LARP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 582 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LARP7 antibody (ABIN2779104)

Egloff, Vitali, Tellier, Raffel, Murphy, Kiss: "The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression." in: The EMBO journal, Vol. 36, Issue 7, pp. 934-948, (2017) (PubMed).

Muniz, Egloff, Kiss: "RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP." in: Nucleic acids research, Vol. 41, Issue 8, pp. 4686-98, (2013) (PubMed).

Target Details for LARP7

Target: LARP7 (La Ribonucleoprotein Domain Family, Member 7 (LARP7))

Alternative Name: LARP7

Background: The function remains unknown.
Alias Symbols: DKFZP564K112, HDCMA18P, MGC104360, PIP7S
Protein Interaction Partner: HEXIM1, AFF1, CDK9, CCNT1, UBC, LIN28B, LIN28A, MEPCE, RNF2, VCPIP1, RABEP2, BRCC3, RPP25, CD2AP, JMJD6, HNRNPR, TRIM28, HUWE1, MTA2, SPAG9, TSC22D1, HDAC1, NR3C1, RN7SK, RPS16, HNRNPA1, CSNK2A1, tat, PAXIP1, BARD1, APP, CAND1, SIRT7, PRPF40A, Ybx1, Nhp2l
Protein Size: 582

Molecular Weight: 67 kDa

Gene ID: 51574

NCBI Accession: NM_015454, NP_056269

UniProt: Q4G0J3

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection