SMARCA5 antibody (N-Term)

Catalog No. ABIN2779246

This Rabbit Polyclonal antibody specifically detects SMARCA5 in WB and ChIP. It exhibits reactivity toward Human, Mouse, Rat, Horse, Cow, Dog and Guinea Pig.

Quick Overview for SMARCA5 antibody (N-Term) (ABIN2779246)

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCA5 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-SMARCA5 Antibody

Binding Specificity: N-Term

Sequence: AGPADAEMEE IFDDASPGKQ KEIQEPDPTY EEKMQTDRAN RFEYLLKQTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SMARCA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1052 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMARCA5

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Alternative Name: SMARCA5

Background: SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ISWI, SNF2H, WCRF135, hISWI, hSNF2H
Protein Interaction Partner: SUMO2, SUMO3, HIST1H3A, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, HB-1, AT5G35210, LMNA, RSF1, BAZ1A, SMARCA5, WHSC1, SS18, SSX2, UL29, RNF168, VCP, NOTCH1, IK, HDAC2, HDAC1, CHRAC1, MBD3, PHGDH, NCSTN, POLR3A, RUVBL2, RBM14, SAP18, HNRNPR, EIF4A3, B
Protein Size: 1052

Molecular Weight: 122 kDa

Gene ID: 8467

NCBI Accession: NM_003601, NP_003592

UniProt: O60264

Pathways: Chromatin Binding