GLIS2 antibody (N-Term)

Catalog No. ABIN2779249

There is 1 publication for this product available. The Rabbit Polyclonal anti-GLIS2 antibody is suitable to detect GLIS2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for GLIS2 antibody (N-Term) (ABIN2779249)

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GLIS2 Antibody

Binding Specificity: N-Term

Purpose: GLIS2 Antibody - N-terminal region

Sequence: QDLVDHVNDY HVKPEKDAGY CCHWEGCARH GRGFNARYKM LIHIRTHTNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GLIS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30037-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GLIS2 antibody (ABIN2779249)

Attanasio, Uhlenhaut, Sousa, OToole, Otto, Anlag, Klugmann, Treier, Helou, Sayer, Seelow, Nürnberg, Becker, Chudley, Nürnberg, Hildebrandt, Treier: "Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis." in: Nature genetics, Vol. 39, Issue 8, pp. 1018-24, (2007) (PubMed).

Target Details for GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Alternative Name: GLIS2

Background:

Background Information: Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.

Gene Name: GLIS family zinc finger 2

Alternative Symbols: NKL, NPHP7

Protein Name: Zinc finger protein GLIS2

Molecular Weight: 56 kDa

Gene ID: 84662

NCBI Accession: NP_115964

UniProt: Q9BZE0