GLIS2 antibody (N-Term)

Catalog No. ABIN2779249

The Rabbit Polyclonal anti-GLIS2 antibody has been validated for WB and IHC. It is suitable to detect GLIS2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for GLIS2 antibody (N-Term) (ABIN2779249)

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GLIS2 Antibody

Binding Specificity: N-Term

Sequence: QDLVDHVNDY HVKPEKDAGY CCHWEGCARH GRGFNARYKM LIHIRTHTNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GLIS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GLIS2 antibody (ABIN2779249)

Attanasio, Uhlenhaut, Sousa, OToole, Otto, Anlag, Klugmann, Treier, Helou, Sayer, Seelow, Nürnberg, Becker, Chudley, Nürnberg, Hildebrandt, Treier: "Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis." in: Nature genetics, Vol. 39, Issue 8, pp. 1018-24, (2007) (PubMed).

Target Details for GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Alternative Name: GLIS2

Background: Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.
Alias Symbols: NKL, NPHP7
Protein Interaction Partner: TRIM32, UBC, PML, BBS2, BBS1, WNK1, XAB2, GPSM2, CPSF1, RBFOX2, SPECC1L, U2AF2, CTNNB1,
Protein Size: 524

Molecular Weight: 56 kDa

Gene ID: 84662

NCBI Accession: NM_032575, NP_115964

UniProt: Q9BZE0