KLF11 antibody (N-Term)

Catalog No. ABIN2779252

This Rabbit Polyclonal antibody specifically detects KLF11 in WB. It exhibits reactivity toward Human, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig and Pig.

Quick Overview for KLF11 antibody (N-Term) (ABIN2779252)

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Reactivity: Human, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLF11 Antibody

Binding Specificity: N-Term

Purpose: KLF11 Antibody - N-terminal region

Sequence: SQKGDLLRIR PLTPVSDSGD VTTTVHMDAA TPELPKDFHS LSTLCITPPQ

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 77%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against KLF11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104029

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLF11

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Alternative Name: KLF11

Background:

Background Information: KLF11 (TIEG2) is a pancreas-enriched transcription factor that has elicited significant attention because of its role as negative regulator of exocrine cell growth in vitro and in vivo. It plays a role in the regulation of pancreatic beta cell physiology, and its variants may contribute to the development of diabetes.

Gene Name: Kruppel-like factor 11

Alternative Symbols: FKLF, FKLF1, MODY7, TIEG2, Tieg3

Protein Name: Krueppel-like factor 11

Molecular Weight: 55kDa

Gene ID: 8462

NCBI Accession: NP_003588

UniProt: O14901