ELL antibody (Middle Region)

Catalog No. ABIN2779278

This Rabbit Polyclonal antibody specifically detects ELL in WB. It exhibits reactivity toward Human and Dogand has been mentioned in 1 publication.

Quick Overview for ELL antibody (Middle Region) (ABIN2779278)

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ELL Antibody

Binding Specificity: Middle Region

Sequence: TDCAQPSRPH GSPSRSKPKK KSKKHKDKER AAEDKPRAQL PDCAPATHAT

Predicted Reactivity: Dog: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ELL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ELL antibody (ABIN2779278)

Wang, Xu, Han, Shi, Luo, Jiang, Lin, Huang, Xia, Guan: "High incidence of hepatitis B virus infection in B-cell subtype non-Hodgkin lymphoma compared with other cancers." in: Cancer, Vol. 109, Issue 7, pp. 1360-4, (2007) (PubMed).

Target Details for ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Alternative Name: ELL

Background: ELL ia an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
Alias Symbols: C19orf17, DKFZp434I1916, ELL1, Men, MEN, PPP1R68
Protein Interaction Partner: UBC, LOC100363176, SNF8, MCM2, Polr2e, Polr2l, Polr2h, Polr2d, Polr2a, Polr2c, Polr2i, Polr2b, Polr2j, Polr2g, Polr2f, EAF1, ICE2, AFF4, PPP1CA, ICE1, MED26, MLLT3, CDK9, TFPT, KMT2A, MLLT1, USPL1, EAF2, HNRNPU, TP53, ZHX1, SIRT2,
Protein Size: 621

Molecular Weight: 68 kDa

Gene ID: 8178

NCBI Accession: NM_006532, NP_006523

UniProt: P55199