ELL antibody

Catalog No. ABIN7183500

Product Details anti-ELL Antibody

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human ELL.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Alternative Name: ELL (ELL Products)

Synonyms: wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody

Background:

Background: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).
Simone F., Blood 98:201-209(2001).
Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005).

Aliases: ELL antibody, C19orf17RNA polymerase II elongation factor ELL antibody, Eleven-nineteen lysine-rich leukemia protein antibody

UniProt: P55199