CDK2 antibody (Middle Region)

Catalog No. ABIN2779325

This anti-CDK2 antibody is a Rabbit Polyclonal antibody detecting CDK2 in WB and IHC. Suitable for Human, Mouse, Rat, Rabbit, Cow, Sheep, Zebrafish (Danio rerio), Goat and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for CDK2 antibody (Middle Region) (ABIN2779325)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Sheep, Zebrafish (Danio rerio), Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDK2 Antibody

Binding Specificity: Middle Region

Sequence: VLHRDLKPQN LLINTEGAIK LADFGLARAF GVPVRTYTHE VVTLWYRAPE

Predicted Reactivity: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDK2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CDK2 antibody (ABIN2779325)

Huang, Chen, Wu, Huang, He, Tang, Wang, Wang: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: Phospho-cdk2 (Thr160) probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Alias Symbols: p33(CDK2)
Protein Interaction Partner: MAPT, CDKN1A, CCNA2, VCP, SAMHD1, IMPDH2, CDK2, SKP1, FZR1, CKS2, CKS1B, CCNE2, GOLGA2, CREBBP, CDKN1C, CDKN1B, CCNE1, CDK13, SKP2, RBL2, RBL1, CCNB1, COPS5, PTMA, HIST1H1A, PRDX1, CCNJ, CDK7, CDK3, EP300, ATP1A1, MYBL2, MNAT1, HSPD1, HSP90AB1, HSP90AA1,
Protein Size: 298

Molecular Weight: 34 kDa

Gene ID: 1017

NCBI Accession: NM_001798, NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA