ETS1 antibody (Middle Region)

Catalog No. ABIN2779338

The Rabbit Polyclonal anti-ETS1 antibody is suitable to detect ETS1 in samples from Human, Mouse, Rat, Dog, Rabbit, Cow, Pig, Goat, Horse and Guinea Pig. It has been validated for WB.

Quick Overview for ETS1 antibody (Middle Region) (ABIN2779338)

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Pig, Goat, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ETS1 Antibody

Binding Specificity: Middle Region

Purpose: ETS1 Antibody - middle region

Sequence: FQKFCMNGAA LCALGKDCFL ELAPDFVGDI LWEHLEILQK EDVKPYQVNG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ETS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ETS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30499-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ETS1

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Alternative Name: ETS1

Background:

Background Information: This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: v-ets avian erythroblastosis virus E26 oncogene homolog 1

Alternative Symbols: p54, ETS-1, EWSR2, c-ets-1

Protein Name: protein C-ets-1

Molecular Weight: 29kDa

Gene ID: 2113

NCBI Accession: NP_001137292

UniProt: Q96AC5