Nkx2-2 antibody (N-Term)

Catalog No. ABIN2779437

The Rabbit Polyclonal anti-Nkx2-2 antibody has been validated for WB. It is suitable to detect Nkx2-2 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Sheep and Pig.

Quick Overview for Nkx2-2 antibody (N-Term) (ABIN2779437)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Sheep, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nkx2-2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nkx2-2 Antibody

Binding Specificity: N-Term

Sequence: GLAAGAPPQD SSSKSPEPSA DESPDNDKET PGGGGDAGKK RKRRVLFSKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against NKX2-2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NKX2-2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Alternative Name: NKX2-2

Background: Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.
Alias Symbols: NKX2.2, NKX2B
Protein Interaction Partner: Dlg4, SIN3A, HDAC1, OLIG2,
Protein Size: 273

Molecular Weight: 30 kDa

Gene ID: 4821

NCBI Accession: NM_002509, NP_002500

UniProt: O95096

Pathways: Dopaminergic Neurogenesis