PCSK6 antibody (N-Term)

Catalog No. ABIN2779442

The Rabbit Polyclonal anti-PCSK6 antibody (ABIN2779442) specifically detects PCSK6 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Pig, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for PCSK6 antibody (N-Term) (ABIN2779442)

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Reactivity: Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Pig, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCSK6 Antibody

Binding Specificity: N-Term

Sequence: IYSASWGPDD DGKTVDGPGR LAKQAFEYGI KKGRQGLGSI FVWASGNGGR

Predicted Reactivity: Cow: 77%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against PCSK6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 623 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCSK6

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Alternative Name: PCSK6

Background: PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.
Alias Symbols: SPC4, PACE4
Protein Interaction Partner: env, UBC, CACNA1A, RCN3, FLG, PMCH, PCSK6,
Protein Size: 623

Molecular Weight: 68 kDa

Gene ID: 5046

NCBI Accession: NM_138323, NP_612196

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome