ATF6B antibody (N-Term)

Catalog No. ABIN2779487

The Rabbit Polyclonal anti-ATF6B antibody is suitable to detect ATF6B in samples from Human, Mouse, Rat, Pig, Cow, Horse and Guinea Pig. It has been validated for WB.

Quick Overview for ATF6B antibody (N-Term) (ABIN2779487)

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivity: Human, Mouse, Rat, Pig, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF6B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATF6B Antibody

Binding Specificity: N-Term

Purpose: CREBL1 Antibody - N-terminal region

Sequence: EIADPTRFFT DNLLSPEDWG LQNSTLYSGL DEVAEEQTQL FRCPEQDVPF

Predicted Reactivity: Cow: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CREBL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREBL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093912

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATF6B

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Alternative Name: CREBL1

Background:

Background Information: CREBL1 bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.

Gene Name: Activating transcription factor 6 beta

Alternative Symbols: G13, CREBL1, CREB-RP

Protein Name: Cyclic AMP-dependent transcription factor ATF-6 beta

Molecular Weight: 77kDa

Gene ID: 1388

NCBI Accession: NP_004372

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction