GSC antibody (N-Term)

Catalog No. ABIN2779490

Cited in 1 publication. The Rabbit Polyclonal anti-GSC antibody (ABIN2779490) specifically detects GSC in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog and Pig samples.

Quick Overview for GSC antibody (N-Term) (ABIN2779490)

Target: GSC (Goosecoid Homeobox (GSC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GSC Antibody

Binding Specificity: N-Term

Purpose: GSC Antibody - N-terminal region

Sequence: FPALHGDSLY GASGGASSDY GAFYPRPVAP GGAGLPAAVS GSRLGYNNYF

Predicted Reactivity: Cow: 86%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against GSC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101868

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GSC antibody (ABIN2779490)

Behl, Hsieh, Shafer, Mundy, Rice, Boyd, Freedman, Hunter, Jarema, Padilla, Tice: "Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity." in: Neurotoxicology and teratology, Vol. 52, Issue Pt B, pp. 181-93, (2015) (PubMed).

Target Details for GSC

Target: GSC (Goosecoid Homeobox (GSC))

Alternative Name: GSC

Background:

Background Information: GSC regulates chordin (CHRD). GSC may play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.

Gene Name: Goosecoid homeobox

Alternative Symbols: SAMS

Protein Name: Homeobox protein goosecoid

Molecular Weight: 28kDa

Gene ID: 145258

NCBI Accession: NP_776248

UniProt: P56915