DLX3 antibody (N-Term)

Catalog No. ABIN2779508

The Rabbit Polyclonal anti-DLX3 antibody (ABIN2779508) specifically detects DLX3 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Guinea Pig and Rabbit samples.

Quick Overview for DLX3 antibody (N-Term) (ABIN2779508)

Target: DLX3 (Distal-Less Homeobox 3 (DLX3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DLX3 Antibody

Binding Specificity: N-Term

Purpose: DLX3 Antibody - N-terminal region

Sequence: SSILTDISSS LSCHAGSKDS PTLPESSVTD LGYYSAPQHD YYSGQPYGQT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against DLX3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLX3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098995

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLX3

Target: DLX3 (Distal-Less Homeobox 3 (DLX3))

Alternative Name: DLX3

Background:

Background Information: DLX3 is a member of the Dlx gene family which contains a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less homeo box(Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.

Gene Name: Distal-less homeobox 3

Alternative Symbols: AI4, TDO

Protein Name: Homeobox protein DLX-3

Molecular Weight: 32kDa

Gene ID: 1747

NCBI Accession: NP_005211

UniProt: O60479