Aryl Hydrocarbon Receptor antibody (N-Term)

Catalog No. ABIN2779518

This anti-Aryl Hydrocarbon Receptor antibody is a Rabbit Polyclonal antibody detecting Aryl Hydrocarbon Receptor in WB and IHC. Suitable for Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig and Sheep.

Quick Overview for Aryl Hydrocarbon Receptor antibody (N-Term) (ABIN2779518)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: N-Term

Sequence: RAKSFFDVAL KSSPTERNGG QDNCRAANFR EGLNLQEGEF LLQALNGFVL

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against AHR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AHR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 848 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background: AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
Alias Symbols: bHLHe76
Protein Interaction Partner: GNA13, UBC, NFE2L2, MAF, RB1, EP300, ARNT, NCOA2, NCOA1, TBP, TAF9, TAF6, TAF4, NCOA7, NCOR2, BRCA1, IVNS1ABP, AIP, STUB1, AHR, FOXA1, SUMO2, DDB1, CTNNB1, TAF7, PTGES3, SMARCA4, NEDD8, XPO1, ARNTL, CCNT1, NRIP1, DAP3, AR, CUL4B, GTF2F2, RELA, HSP90AA1, E
Protein Size: 848

Molecular Weight: 96 kDa

Gene ID: 196

NCBI Accession: NM_001621, NP_001612

UniProt: P35869

Pathways: Regulation of Cell Size