Elf4 antibody (C-Term)

Catalog No. ABIN2779521

The Rabbit Polyclonal anti-Elf4 antibody is suitable to detect Elf4 in samples from Human, Mouse, Rat, Pig, Cow, Dog, Horse and Rabbit. It has been validated for WB.

Quick Overview for Elf4 antibody (C-Term) (ABIN2779521)

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Elf4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Elf4 Antibody

Binding Specificity: C-Term

Purpose: ELF4 Antibody - C-terminal region

Sequence: VTGAPMEGLL VPEETLRELL RDQAHLQPLP TQVVSRGSHN PSLLGNQTLS

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ELF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ELF4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099383

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Alternative Name: ELF4

Background:

Background Information: ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.

Gene Name: E74-like factor 4 (ets domain transcription factor)

Alternative Symbols: MEF, ELFR

Protein Name: ETS-related transcription factor Elf-4

Molecular Weight: 71kDa

Gene ID: 2000

NCBI Accession: NP_001412

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity