RUVBL2 antibody (N-Term)

Catalog No. ABIN2779601

The Rabbit Polyclonal anti-RUVBL2 antibody has been validated for WB and IHC. It is suitable to detect RUVBL2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for RUVBL2 antibody (N-Term) (ABIN2779601)

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUVBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RUVBL2 Antibody

Binding Specificity: N-Term

Sequence: IDRPATGTGS KVGKLTLKTT EMETIYDLGT KMIESLTKDK VQAGDVITID

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 463 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RUVBL2 antibody (ABIN2779601)

Barthéléry, Jaishankar, Salli, Vrana: "Reptin52 expression during in vitro neural differentiation of human embryonic stem cells." in: Neuroscience letters, Vol. 452, Issue 1, pp. 47-51, (2009) (PubMed).

Target Details for RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Alternative Name: RUVBL2

Background: RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities.
Alias Symbols: RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B
Protein Interaction Partner: CCDC103, LNX1, RUVBL1, UBC, DPCD, HUWE1, VCP, SUMO2, RPAP3, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, CDKN2A, ASNA1, PPP6R3, PLA2G4A, PARK2, FBXO6, TARDBP, YWHAQ, PPP6R2, EXOSC10, BAG3, POLR2E, UPF1, SMG1, RBM8A, TTI1, PAN2, TBP, CTNNB1, STOM, RUVBL
Protein Size: 463

Molecular Weight: 51 kDa

Gene ID: 10856

NCBI Accession: NM_006666, NP_006657

UniProt: Q9Y230

Pathways: Telomere Maintenance