SIRT7 antibody (C-Term)

Catalog No. ABIN2779623

This anti-SIRT7 antibody is a Rabbit Polyclonal antibody detecting SIRT7 in WB. Suitable for Human, Rat, Mouse, Dog, Cow, Horse, Pig and Guinea Pig.

Quick Overview for SIRT7 antibody (C-Term) (ABIN2779623)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIRT7 Antibody

Binding Specificity: C-Term

Sequence: DVMRLLMAEL GLEIPAYSRW QDPIFSLATP LRAGEEGSHS RKSLCRSREE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SIRT7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 400 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Alternative Name: SIRT7

Background: SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
Alias Symbols: SIR2L7
Protein Interaction Partner: DDB1, VPRBP, APP, NOL6, YTHDC2, DDX31, RBM15, ANAPC1, NSD1, NOC3L, UBE2O, RBM25, CCAR2, CHD8, BEND3, PHRF1, DHX37, NUFIP2, CGN, XPO5, LRRC47, BIRC6, WDR18, THOC2, NUP107, REXO4, DDX24, XAB2, UGGT1, ZC3HAV1, YLPM1, NKRF, CCT5, SNW1, DHX30, DIS3, PUF60, COP
Protein Size: 400

Molecular Weight: 45 kDa

Gene ID: 51547

NCBI Accession: NM_016538, NP_057622

UniProt: Q9NRC8