NEUROD6 antibody (Middle Region)

Catalog No. ABIN2779630

This Rabbit Polyclonal antibody specifically detects NEUROD6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Pig and Guinea Pig.

Quick Overview for NEUROD6 antibody (Middle Region) (ABIN2779630)

Target: NEUROD6 (Neurogenic Differentiation 6 (NEUROD6))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEUROD6 Antibody

Binding Specificity: Middle Region

Purpose: NEUROD6 Antibody - middle region

Sequence: RSPYSTFYPP YHSPELTTPP GHGTLDNSKS MKPYNYCSAY ESFYESTSPE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NEUROD6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEUROD6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32417-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEUROD6

Target: NEUROD6 (Neurogenic Differentiation 6 (NEUROD6))

Alternative Name: NEUROD6

Background:

Background Information: NEUROD6 contains 1 basic helix-loop-helix (bHLH) domain. It activates E box-dependent transcription in collaboration with TCF3/E47 and may be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. It transactivates the promoter of its own gene.NEUROD6 is a member of the NEUROD (NEUROD1, MIM 601724) family of basic helix-loop-helix (bHLH) transcription factors (Guo et al., 2002 [PubMed 12357074]).[supplied by OMIM].

Gene Name: Neuronal differentiation 6

Alternative Symbols: Nex1, Atoh2, MATH2, NEX1M, Math-2, bHLHa2

Protein Name: Neurogenic differentiation factor 6

Molecular Weight: 39kDa

Gene ID: 63974

NCBI Accession: NP_073565

UniProt: Q96NK8