LHX4 antibody (LIM Homeobox 4) (Middle Region)

Details for Product anti-LHX4 Antibody No. ABIN2779632, Supplier: Log in to see
Antigen
  • LHX4
  • si:dkeyp-35f11.3
  • CPHD4
  • A330062J17Rik
  • Gsh-4
  • Gsh4
  • LIM homeobox 4
  • LIM homeobox protein 4
  • LHX4
  • lhx4
  • Lhx4
Epitope
Middle Region
18
11
9
8
7
7
7
5
4
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
64
6
3
2
2
2
2
2
1
1
1
1
Host
Rabbit
33
31
Clonality
Polyclonal
Conjugate
This LHX4 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
55
38
12
7
7
3
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human LHX4
Blocking Peptide Blocking peptide for this product available: ABIN979301
Sequence GSFSMDGTGQ SYQDLRDGSP YGIPQSPSSI SSLPSHAPLL NGLDYTVDSN
Predicted Reactivity Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against LHX4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name LHX4 (LHX4 Antibody Abstract)
Background LHX4 is a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects.This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Gsh-4, Gsh4, CPHD4
Protein Interaction Partner: FDX1L, LONRF1, TXNDC5, SNRNP25, CHCHD2, ORC6, USP2, SH2D1A, LDB2, SSX1, ISL1, IFT172,
Protein Size: 390
Molecular Weight 43 kDa
Gene ID 89884
NCBI Accession NM_033343, NP_203129
UniProt P53776
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 390 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-LIM Homeobox 4 (LHX4) (Middle Region) antibody (ABIN2779632) WB Suggested Anti-LHX4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Pfaeffle, Hunter, Savage, Duran-Prado, Mullen, Neeb, Eiholzer, Hesse, Haddad, Stobbe, Blum, Weigel, Rhodes: "Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 3, pp. 1062-71, 2008 (PubMed).

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