LHX3 antibody (Middle Region)

Catalog No. ABIN2779647

Product Details anti-LHX3 Antibody

Target: LHX3 (LIM Homeobox 3 (LHX3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Zebrafish (Danio rerio), Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PSGAPGGPPP MRVLAGNGPS SDLSTGSSGG YPDFPASPAS WLDEVDHAQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LHX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LHX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LHX3

Target: LHX3 (LIM Homeobox 3 (LHX3))

Alternative Name: LHX3 (LHX3 Products)

Synonyms: CPHD3 antibody, LIM3 antibody, M2-LHX3 antibody, lim3 antibody, LIM-3 antibody, xlim-3 antibody, lim-3 antibody, Lim3 antibody, P-LIM antibody, mLIM3 antibody, mLim-3 antibody, lim homeobox 3 antibody, LIM/homeobox protein Lhx3 antibody, LIM homeobox 3 antibody, LIM homeobox 3 L homeolog antibody, LIM homeobox protein 3 antibody, LOC662120 antibody, LOC100224079 antibody, LHX3 antibody, Lhx3 antibody, lhx3 antibody, lhx3.L antibody

Background: LHX3 encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp762A2013, M2-LHX3, LIM3, CPHD3
Protein Interaction Partner: ISL2, IFT172, LDB1, CITED2, ISL1, RLIM, LMX1A, LHX1,
Protein Size: 402

Molecular Weight: 44 kDa

Gene ID: 8022

NCBI Accession: NM_014564, NP_055379

UniProt: Q5TB40