PSMD14 antibody (N-Term)

Catalog No. ABIN2779653

The Rabbit Polyclonal anti-PSMD14 antibody is suitable to detect PSMD14 in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit and Dog. It has been validated for WB and IHC.

Quick Overview for PSMD14 antibody (N-Term) (ABIN2779653)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PSMD14 Antibody

Binding Specificity: N-Term

Sequence: MDRLLRLGGG MPGLGQGPPT DAPAVDTAEQ VYISSLALLK MLKHGRAGVP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PSMD14. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 310 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Alternative Name: PSMD14

Background: POH1 (pad one homolog-1) is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997 [PubMed 9374539]).
Alias Symbols: PAD1, POH1, RPN11
Protein Interaction Partner: FAM9B, DPY30, HUWE1, UBC, PSMD7, MEOX2, UBE3C, SHFM1, UBE3A, RAD23B, PSME2, PSME1, PSMD13, PSMD12, PSMD11, PSMD10, PSMD8, PSME4, ADRM1, PSME3, PSMD6, PSMD4, PSMD3, PSMD2, PSMD1, PSMC6, PSMC5, PSMC4, PSMC3, PSMC2, PSMC1, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3,
Protein Size: 310

Molecular Weight: 35 kDa

Gene ID: 10213

NCBI Accession: NM_005805, NP_005796

UniProt: O00487

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway