COLEC12 antibody (Middle Region)

Catalog No. ABIN2779674

The Rabbit Polyclonal anti-COLEC12 antibody (ABIN2779674) specifically detects COLEC12 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit and Guinea Pig samples.

Quick Overview for COLEC12 antibody (Middle Region) (ABIN2779674)

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COLEC12 Antibody

Binding Specificity: Middle Region

Purpose: COLEC12 Antibody - middle region

Sequence: GLGGDGGGCG GGGSGGGGAP RREPVPFPSG SAGPGPRGPR ATESGKRMDC

Predicted Reactivity: Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against COLEC12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COLEC12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097832

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COLEC12

Background:

Background Information: COLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.

Gene Name: Collectin sub-family member 12

Alternative Symbols: CLP1, NSR2, SRCL, SCARA4

Protein Name: Collectin-12

Molecular Weight: 82kDa

Gene ID: 81035

NCBI Accession: NP_569057

UniProt: Q5KU26

Pathways: Activation of Innate immune Response