CIC antibody (N-Term)

Catalog No. ABIN2779683

The Rabbit Polyclonal anti-CIC antibody has been validated for WB and IHC. It is suitable to detect CIC in samples from Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. There is 1 publication available.

Quick Overview for CIC antibody (N-Term) (ABIN2779683)

Target: CIC (Capicua Homolog (CIC))

Reactivity: Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CIC Antibody

Binding Specificity: N-Term

Sequence: PSQPDPSVQP SEAQQPASHP VASNQSKEPA ESAAVAHERP PGGTGSADPE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CIon Channel. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1608 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CIC antibody (ABIN2779683)

Lee, Chan, Cheung, Cheng, Appleby, Orme, Scotting: "CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons." in: Brain research. Molecular brain research, Vol. 106, Issue 1-2, pp. 151-6, (2002) (PubMed).

Target Details for CIC

Target: CIC (Capicua Homolog (CIC))

Alternative Name: CIC

Background: CIon Channel represents a new subfamily of the HMG-box superfamily. Expression of the Cic gene is predominantly restricted to immature granule cells in the cerebellum, hippocampus and olfactory bulb in the CNS
Protein Interaction Partner: GTPBP3, CENPJ, ZNRD1, PYCR2, SETD2, TRIM22, PICK1, SEC62, ATXN1, GABPB1, PLK1, CSNK2B, NFYC,
Protein Size: 1608

Molecular Weight: 164 kDa

Gene ID: 23152

NCBI Accession: NM_015125, NP_055940

UniProt: Q96RK0