TAF5L antibody (Middle Region)

Catalog No. ABIN2779726

This Rabbit Polyclonal antibody specifically detects TAF5L in WB. It exhibits reactivity toward Human, Mouse, Dog, Rabbit, Rat, Guinea Pig, Horse, Cow and Zebrafish (Danio rerio).

Quick Overview for TAF5L antibody (Middle Region) (ABIN2779726)

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Reactivity: Human, Mouse, Dog, Rabbit, Rat, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF5L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAF5L Antibody

Binding Specificity: Middle Region

Sequence: CVKFHPNSNY LATGSTDKTV RLWSAQQGNS VRLFTGHRGP VLSLAFSPNG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TAF5L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TAF5L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 589 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF5L

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Alternative Name: TAF5L

Background: TAF5L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: PAF65B
Protein Interaction Partner: HECW2, UBC, KAT2B, LSM11, TADA3, TAF10, ELAVL1, TSC22D1, TTR, H2AFX, CDKN1A, ANXA7, KAT2A, TP53, ATXN7, CEBPE, USP22, ATXN7L3, SUPT3H, TAF9, MYC,
Protein Size: 589

Molecular Weight: 66 kDa

Gene ID: 27097

NCBI Accession: NM_014409, NP_055224

UniProt: O75529