HOXC11 antibody (Middle Region)

Catalog No. ABIN2779771

This Rabbit Polyclonal antibody specifically detects HOXC11 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit and Dog.

Quick Overview for HOXC11 antibody (Middle Region) (ABIN2779771)

Target: HOXC11 (Homeobox C11 (HOXC11))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXC11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HOXC11 Antibody

Binding Specificity: Middle Region

Purpose: HOXC11 Antibody - middle region

Sequence: DRFFDNAYCG GGDPPAEPPC SGKGEAKGEP EAPPASGLAS RAEAGAEAEA

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXC11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102723

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXC11

Target: HOXC11 (Homeobox C11 (HOXC11))

Alternative Name: HOXC11

Background:

Background Information: HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

Gene Name: Homeobox C11

Alternative Symbols: HOX3H

Protein Name: Homeobox protein Hox-C11

Molecular Weight: 34kDa

Gene ID: 3227

NCBI Accession: NP_055027

UniProt: O43248