EGR1 antibody (N-Term)

Catalog No. ABIN2779828

This Rabbit Polyclonal antibody specifically detects EGR1 in WB and IHC. It exhibits reactivity toward Mouse, Rat, Horse, Cow, Dog, Rabbit, Sheep and Pig.

Quick Overview for EGR1 antibody (N-Term) (ABIN2779828)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reactivity: Mouse, Rat, Horse, Cow, Dog, Rabbit, Sheep, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EGR1 Antibody

Binding Specificity: N-Term

Sequence: GTPEGSGGNS SSSTSSGGGG GGGSNSGSSA FNPQGEPSEQ PYEHLTTESF

Predicted Reactivity: Cow: 92%, Dog: 75%, Horse: 85%, Mouse: 100%, Pig: 85%, Rabbit: 77%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse EGR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 533 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Alternative Name: EGR1

Background: Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
Alias Symbols: egr, TIS8, Zenk, Egr-1, NGFIA, Zfp-6, ETR103, Krox-1, Krox24, NGF1-A, NGFI-A, Zif268, Krox-24, A530045N19Rik
Protein Interaction Partner: Sp1, Pin1, Sf1, Pitx1, Nab2, Egr1, G3bp1, Srf, Smarca4, Elk1, Hist4h4, Nelfe, Tbp, Gtf2b, Cdk8,
Protein Size: 533

Molecular Weight: 59 kDa

Gene ID: 13653

NCBI Accession: NM_007913, NP_031939

UniProt: P08046

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity