GCM1 antibody (N-Term)

Catalog No. ABIN2779842

There is 1 publication for this product available. The Rabbit Polyclonal anti-GCM1 antibody is suitable to detect GCM1 in samples from Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for GCM1 antibody (N-Term) (ABIN2779842)

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GCM1 Antibody

Binding Specificity: N-Term

Purpose: Gcm1 Antibody - N-terminal region

Sequence: KEILSWDIND VKLPQNVKTT DWFQEWPDSY VKHIYSSDDR NAQRHLSSWA

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 86%, Mouse: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Gcm1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Gcm1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36863-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GCM1 antibody (ABIN2779842)

Zhang, Muralimanoharan, Wortman, Mendelson: "Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia." in: Proceedings of the National Academy of Sciences of the United States of America, (2016) (PubMed).

Target Details for GCM1

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Alternative Name: Gcm1

Background:

Background Information: Transcription factor that is necessary for placental development

Gene Name: Glial cells missing homolog 1 (Drosophila)

Alternative Symbols: GCM, gli, GCMa, glide, Gcm1-r, Gcm-rs2, Gcm1-rs1

Protein Name: Chorion-specific transcription factor GCMa

Molecular Weight: 49kDa

Gene ID: 14531

NCBI Accession: NP_032129

UniProt: P70348