NK2 Homeobox 3 antibody (C-Term)

Catalog No. ABIN2779879

The Rabbit Polyclonal anti-NK2 Homeobox 3 antibody (ABIN2779879) specifically detects NK2 Homeobox 3 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow and Guinea Pig samples.

Quick Overview for NK2 Homeobox 3 antibody (C-Term) (ABIN2779879)

Target: NK2 Homeobox 3 (NKX2-3)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NK2 Homeobox 3 Antibody

Binding Specificity: C-Term

Purpose: Nkx2-3 Antibody - C-terminal region

Sequence: AAAYSGSYGC AYPTGGGGGG GGTASAATTA MQPACSATGG GSFVNVSNLG

Predicted Reactivity: Cow: 87%, Guinea Pig: 87%, Human: 87%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Nkx2-3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Nkx2-3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36944-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NK2 Homeobox 3

Target: NK2 Homeobox 3 (NKX2-3)

Alternative Name: Nkx2-3

Background:

Background Information: Nkx2-3 is a transcriptional regulator essential for normal development and functions of the small intestine and spleen.Nkx2-3 activates directly MADCAM1 expression.Nkx2-3 is required for homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. Nkx2-3 may have a role during pharyngeal organogenesis.

Gene Name: NK2 transcription factor related, locus 3 (Drosophila)

Alternative Symbols: ti, Nkx2., Nkx-2., Nkx2.3, nkx2-C, tinman, Nkx-2.3

Protein Name: Homeobox protein Nkx-2.3

Molecular Weight: 38 kDa

Gene ID: 18089

NCBI Accession: NP_032725

UniProt: P97334