NK2 Homeobox 5 antibody (N-Term)
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- Target See all NK2 Homeobox 5 (NKX2-5) Antibodies
- NK2 Homeobox 5 (NKX2-5)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NK2 Homeobox 5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MFPSPALTPT PFSVKDILNL EQQQRSLASG DLSARLEATL APASCMLAAF
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 80%, Mouse: 100%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Nkx2-5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the n terminal region of mouse Nkx2-5
- Top Product
- Discover our top product NKX2-5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 318 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NK2 Homeobox 5 (NKX2-5)
- Alternative Name
- Nkx2-5 (NKX2-5 Products)
- Synonyms
- CHNG5 antibody, CSX antibody, CSX1 antibody, HLHS2 antibody, NKX2.5 antibody, NKX2E antibody, NKX4-1 antibody, VSD3 antibody, Csx antibody, Nkx-2.5 antibody, Nkx2.5 antibody, tinman antibody, nk2.5 antibody, nkx2-5 antibody, zgc:111912 antibody, AR2 antibody, XNkx2-5 antibody, csx antibody, nkx-2.5 antibody, nkx2-5b antibody, nkx2.5 antibody, NKX2-5 antibody, Nkx2-5 antibody, csx1 antibody, nkx2e antibody, XNkx-2.5 antibody, CNKX-2.5 antibody, NKX-2.5 antibody, NK2 homeobox 5 antibody, NK2 homeobox 5 S homeolog antibody, NKX2-5 antibody, Nkx2-5 antibody, nkx2.5 antibody, nkx2-5.S antibody, nkx2-5 antibody
- Background
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Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.
Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman
Protein Interaction Partner: Tbx5, Foxh1, Hand2, Hand1, Mef2c, Tbx1, Prox1, Smarca4, SRF,
Protein Size: 318 - Molecular Weight
- 34 kDa
- Gene ID
- 18091
- NCBI Accession
- NM_008700, NP_032726
- UniProt
- P42582
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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