NPAS2 antibody (C-Term)

Catalog No. ABIN2779882

The Rabbit Polyclonal anti-NPAS2 antibody is suitable to detect NPAS2 in samples from Mouse and Rat. It has been validated for WB.

Quick Overview for NPAS2 antibody (C-Term) (ABIN2779882)

Target: NPAS2 (Neuronal PAS Domain Protein 2 (NPAS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPAS2 Antibody

Binding Specificity: C-Term

Purpose: Npas2 Antibody - C-terminal region

Sequence: PLQPAQAQQQ PPPYLQAPTS LHSEQPDSLL LSTFSQQPGT LGYAATQSTP

Predicted Reactivity: Mouse: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against Npas2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36953-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPAS2

Target: NPAS2 (Neuronal PAS Domain Protein 2 (NPAS2))

Alternative Name: Npas2

Background:

Background Information: BMAL1-NPAS2 heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Gene Name: Neuronal PAS domain protein 2

Alternative Symbols: MO, MOP4, bHLHe, bHLHe9

Protein Name: Neuronal PAS domain-containing protein 2

Molecular Weight: 91kDa

Gene ID: 18143

NCBI Accession: NP_032745

UniProt: P97460

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism