NRF2 antibody (N-Term)

Catalog No. ABIN2779961

The Rabbit Polyclonal anti-NRF2 antibody has been validated for WB. It is suitable to detect NRF2 in samples from Human, Mouse, Rat, Dog, Cow, Rabbit and Saccharomyces cerevisiae.

Quick Overview for NRF2 antibody (N-Term) (ABIN2779961)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NRF2 Antibody

Binding Specificity: N-Term

Sequence: DLIDILWRQD IDLGVSREVF DFSQRQKDYE LEKQKKLEKE RQEQLQKEQE

Predicted Reactivity: Cow: 86%, Dog: 79%, Human: 86%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against Nfe2l2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Nfe2l2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 597 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Alternative Name: Nfe2l2

Background: Nfe2l2 is a basic leucine zipper transcription factor, It is involved in activating expression of genes with an antioxidant response element (ARE).
Alias Symbols: -
Protein Interaction Partner: Chd6, Mafk,
Protein Size: 597

Molecular Weight: 65 kDa

Gene ID: 83619

NCBI Accession: NM_031789, NP_113977

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling