CCL5 antibody (Middle Region)

Catalog No. ABIN2779989

The Rabbit Polyclonal anti-CCL5 antibody (ABIN2779989) specifically detects CCL5 in WB. The antibody is reactive with Human, Mouse, Dog, Rat, Cow, Guinea Pig, Pig, Horse and Rabbit samples.

Quick Overview for CCL5 antibody (Middle Region) (ABIN2779989)

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Reactivity: Human, Mouse, Dog, Rat, Cow, Guinea Pig, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCL5 Antibody

Binding Specificity: Middle Region

Purpose: CCL5 Antibody - middle region

Sequence: YGSDTTPCCF AYLSLELPRA HVKEYFYTSS KCSNLAVVFV TRRNRQVCAN

Predicted Reactivity: Cow: 85%, Dog: 91%, Guinea Pig: 85%, Horse: 85%, Human: 85%, Mouse: 100%, Pig: 91%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CCL5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse CCL5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096855

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Alternative Name: CCL5

Background:

Background Information: Recently, it has been shown that genetic polymorphisms can result in diminished expression of CCL5, which results in increased susceptibility to and progression of infectious diseases. CCL5, together with Th cytokine mRNA expression, is temporally up-regulated during pneumococcal carriage. CCL5 is an essential factor for the induction and maintenance of protective pneumococcal immunity

Gene Name: Chemokine (C-C motif) ligand 5

Alternative Symbols: S, RA, Scy, MuRa, SISd, Scya5, TCP22, RANTES, TCP228, MuRantes

Protein Name: C-C motif chemokine 5

Molecular Weight: 10kDa

Gene ID: 20304

NCBI Accession: NP_038681

UniProt: P30882

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration