T-Bet antibody (N-Term)

Catalog No. ABIN2780014

This Rabbit Polyclonal antibody specifically detects T-Bet in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig and Rabbit.

Quick Overview for T-Bet antibody (N-Term) (ABIN2780014)

Target: T-Bet

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Bet antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Bet Antibody

Binding Specificity: N-Term

Sequence: MGIVEPGCGD MLTGTEPMPS DEGRGPGADQ QHRFFYPEPG AQDPTDRRAG

Predicted Reactivity: Cow: 79%, Dog: 79%, Human: 86%, Mouse: 100%, Pig: 79%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Tbx21. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for T-Bet

Target: T-Bet

Alternative Name: Tbx21

Background: Tbx21 is a transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Tbx21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs
Alias Symbols: T-bet, TBT1, Tblym, Tbet
Protein Interaction Partner: Bcl6, Smarca4, Tlx3, Tead4, Pax9, Gsc, Gata3, Dlx1, Alx4, Rbpj, Stat1, Ifng, Tec, Itk, Txk,
Protein Size: 530

Molecular Weight: 58 kDa

Gene ID: 57765

NCBI Accession: NM_019507, NP_062380

UniProt: Q9JKD8