PUS1 antibody (C-Term)

Catalog No. ABIN2780021

This anti-PUS1 antibody is a Rabbit Polyclonal antibody detecting PUS1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for PUS1 antibody (C-Term) (ABIN2780021)

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUS1 Antibody

Binding Specificity: C-Term

Sequence: PTIVSTERDE RSMAQWLNTL PIHNFSGTAL GAADTGAKVP SSLEGSEGDG

Predicted Reactivity: Human: 92%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PUS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 393 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: PUS1

Background: Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.
Alias Symbols: MPUS1, mPus1p, A730013B20Rik
Protein Interaction Partner: Rarg, Sra1, Rarb,
Protein Size: 423

Molecular Weight: 48 kDa

Gene ID: 56361

NCBI Accession: NM_001025562, NP_001020733

UniProt: Q791J1