RUNX3 antibody (C-Term)

Catalog No. ABIN2780022

This Rabbit Polyclonal antibody specifically detects RUNX3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit, Dog and Guinea Pig.

Quick Overview for RUNX3 antibody (C-Term) (ABIN2780022)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RUNX3 Antibody

Binding Specificity: C-Term

Purpose: RUNX3 Antibody - C-terminal region

Sequence: PYPGAPQSQS GPFQANPAPY HLFYGASSGS YQFSMAAAGG GERSPTRMLT

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 79%, Mouse: 100%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RUNX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse RUNX3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111058

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background:

Background Information: RUNX3 belongs to The RUNX family of transcription factors that are important regulators of linage-specific gene expression in major developmental pathways. Runx3 is highly expressed in developing cranial and dorsal root ganglia (DRGs).

Gene Name: Runt related transcription factor 3

Alternative Symbols: AM, Rx, Rx3, AML2, Cbfa, Cbfa3, Pebp2a3

Molecular Weight: 45kDa

Gene ID: 12399

NCBI Accession: NP_062706

UniProt: Q64131