DMBX1 antibody (Middle Region)

Catalog No. ABIN2780096

The Rabbit Polyclonal anti-DMBX1 antibody (ABIN2780096) specifically detects DMBX1 in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Guinea Pig, Dog, Cow, Horse and Rabbit samples.

Quick Overview for DMBX1 antibody (Middle Region) (ABIN2780096)

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Reactivity: Human, Rat, Mouse, Guinea Pig, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMBX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DMBX1 Antibody

Binding Specificity: Middle Region

Purpose: DMBX1 Antibody - middle region

Sequence: LSLSEQSASE SAPEDQLDRE EDSRAEEPKA EKSPGSESKV PGCKRGSPKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DMBX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse DMBX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098870

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DMBX1

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Alternative Name: DMBX1

Background:

Background Information: Transcription factors containing a homeodomain play an important role in the organogenesis of vertebrates. Otx3/Dmbx1 is a member of paired class homeodomain transcription factors. Otx3/Dmbx1 represses the Otx2-mediated transactivation in the developing brain by forming heterodimer with Otx2 on the P3C (TAATCCGATTA) sequence in vitro.

Gene Name: Diencephalon/mesencephalon homeobox 1

Alternative Symbols: At, Atx, Mbx, Otx, Cdmx, Otx3

Protein Name: Diencephalon/mesencephalon homeobox protein 1

Molecular Weight: 41kDa

Gene ID: 140477

NCBI Accession: NP_001020738

UniProt: Q91ZK3

Pathways: Feeding Behaviour