NFAT5 antibody (Middle Region)

Catalog No. ABIN2780105

This Rabbit Polyclonal antibody specifically detects NFAT5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Pig.It has been mentioned in 1 publication

Quick Overview for NFAT5 antibody (Middle Region) (ABIN2780105)

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFAT5 Antibody

Binding Specificity: Middle Region

Sequence: TIQTQDISQP GTFPAVSAAS QLPSSDALLQ QATQFQTREA QSRDTIQSDT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 83%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NFAT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse NFAT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NFAT5 antibody (ABIN2780105)

Bire, Casteret, Piégu, Beauclair, Moiré, Arensbuger, Bigot: "Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2." in: PLoS genetics, Vol. 12, Issue 3, pp. e1005902, (2016) (PubMed).

Target Details for NFAT5

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Alternative Name: NFAT5

Background: Nfat5 contains 1 RHD (Rel-like) domain, and plays a role in the inducible expression of genes. Nfat5 regulates hypertonicity-induced cellular accumulation of osmolytes. Nfat5 might be capable of forming stable dimers with DNA elements
Alias Symbols: CAG-8, CAG80, OREBP, nfatz, NFATL1, TonEBP, AI225870, mKIAA0827, B130038B15Rik
Protein Size: 1534

Molecular Weight: 166 kDa

Gene ID: 54446

NCBI Accession: NM_018823

UniProt: Q9WV30

Pathways: RTK Signaling, WNT Signaling