MKL1 antibody (C-Term)

Catalog No. ABIN2780121

The Rabbit Polyclonal anti-MKL1 antibody (ABIN2780121) specifically detects MKL1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for MKL1 antibody (C-Term) (ABIN2780121)

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MKL1 Antibody

Binding Specificity: C-Term

Purpose: MKL1 Antibody - C-terminal region

Sequence: QPLSQPGFPA PGPPAQMDLE HPPQPPFATP TSLLKKEPPG YEETVTQQPK

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 79%, Mouse: 100%, Pig: 86%, Rabbit: 86%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against MKL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105040

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Alternative Name: MKL1

Background:

Background Information: MKL1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

Gene Name: MKL (megakaryoblastic leukemia)/myocardin-like 1

Alternative Symbols: M, Bs, Mal, Mkl, AMKL, Bsac, MRTF, Mkl1, Mrtf-A

Protein Name: MKL/myocardin-like protein 1

Molecular Weight: 106kDa

Gene ID: 223701

NCBI Accession: NP_694629

UniProt: Q8K4J6