HELT antibody (C-Term)

Catalog No. ABIN2780137

This Rabbit Polyclonal antibody specifically detects HELT in WB. It exhibits reactivity toward Mouse, Human, Rat, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for HELT antibody (C-Term) (ABIN2780137)

Target: HELT (Helt BHLH Transcription Factor (HELT))

Reactivity: Mouse, Human, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HELT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HELT Antibody

Binding Specificity: C-Term

Sequence: LPEPDFSYQL HAASPEFPGH SPGEATMFPQ GATPGSFPWP PGAARSPALP

Predicted Reactivity: Cow: 85%, Guinea Pig: 77%, Horse: 85%, Human: 85%, Mouse: 100%, Rabbit: 77%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Helt. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Helt

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 240 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HELT

Target: HELT (Helt BHLH Transcription Factor (HELT))

Alternative Name: Helt

Background: Helt is a transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3' and is required for the development of GABAergic neurons.
Alias Symbols: A830086M02, Hesl, Mgn, megane
Protein Interaction Partner: Helt, Hey2, Hes5,
Protein Size: 240

Molecular Weight: 27 kDa

Gene ID: 234219

NCBI Accession: NM_173789, NP_776150

UniProt: Q7TS99

Pathways: Feeding Behaviour