HELT antibody (C-Term)

Catalog No. ABIN2780137

This Rabbit Polyclonal antibody specifically detects HELT in WB. It exhibits reactivity toward Mouse, Human, Rat, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for HELT antibody (C-Term) (ABIN2780137)

Target: HELT (Helt BHLH Transcription Factor (HELT))

Reactivity: Mouse, Human, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HELT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HELT Antibody

Binding Specificity: C-Term

Purpose: Helt Antibody - C-terminal region

Sequence: LPEPDFSYQL HAASPEFPGH SPGEATMFPQ GATPGSFPWP PGAARSPALP

Predicted Reactivity: Cow: 85%, Guinea Pig: 77%, Horse: 85%, Human: 85%, Mouse: 100%, Rabbit: 77%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Helt. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Helt

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37537-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HELT

Target: HELT (Helt BHLH Transcription Factor (HELT))

Alternative Name: Helt

Background:

Background Information: Helt is a transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3' and is required for the development of GABAergic neurons.

Gene Name: helt bHLH transcription factor

Alternative Symbols: Mgn, Hesl, mega, megane, Heslike, A830086M02

Protein Name: Hairy and enhancer of split-related protein HELT

Molecular Weight: 27kDa

Gene ID: 234219

NCBI Accession: NP_776150

UniProt: Q7TS99

Pathways: Feeding Behaviour