ZNF146 antibody (Middle Region)

Catalog No. ABIN2780242

Product Details anti-ZNF146 Antibody

Target: ZNF146 (Zinc Finger Protein 146 (ZNF146))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF146 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TEHEKIHIGE KPFKCSECGT AFGQKKYLIK HQNIHTGEKP YECNECGKAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZNF146. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF146

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 292 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF146

Target: ZNF146 (Zinc Finger Protein 146 (ZNF146))

Alternative Name: ZNF146 (ZNF146 Products)

Synonyms: OZF antibody, Znf146 antibody, zinc finger protein 146 antibody, Zfp146 antibody, ZNF146 antibody

Background: ZNF146 (OZF) overexpression in tumours may alter the balance between hRap1 and other telomeric proteins, therefore OZF function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80 % of colorectal cancers.
Alias Symbols: MGC125660, MGC125661, OZF
Protein Interaction Partner: HIPK4, CDK20, UBC, TERF2IP,
Protein Size: 292

Molecular Weight: 33 kDa

Gene ID: 7705

NCBI Accession: NM_007145, NP_009076

UniProt: Q15072