ZNF146 antibody (Middle Region)

Catalog No. ABIN2780242

This Rabbit Polyclonal antibody specifically detects ZNF146 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig, Dog and Rabbit.

Quick Overview for ZNF146 antibody (Middle Region) (ABIN2780242)

Target: ZNF146 (Zinc Finger Protein 146 (ZNF146))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF146 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF146 Antibody

Binding Specificity: Middle Region

Purpose: ZNF146 Antibody - middle region

Sequence: TEHEKIHIGE KPFKCSECGT AFGQKKYLIK HQNIHTGEKP YECNECGKAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZNF146. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF146

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37755-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF146

Target: ZNF146 (Zinc Finger Protein 146 (ZNF146))

Alternative Name: ZNF146

Background:

Background Information: ZNF146 (OZF) overexpression in tumours may alter the balance between hRap1 and other telomeric proteins, therefore OZF function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80 % of colorectal cancers.

Gene Name: Zinc finger protein 146

Alternative Symbols: OZF

Protein Name: Zinc finger protein OZF

Molecular Weight: 33kDa

Gene ID: 7705

NCBI Accession: NP_009076

UniProt: Q15072