TADA2L antibody (Middle Region)

Catalog No. ABIN2780370

This Rabbit Polyclonal antibody specifically detects TADA2L in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for TADA2L antibody (Middle Region) (ABIN2780370)

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA2L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TADA2L Antibody

Binding Specificity: Middle Region

Purpose: TADA2L Antibody - middle region

Sequence: LEYKSALLNE CNKQGGLRLA QARALIKIDV NKTRKIYDFL IREGYITKG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TADA2L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38045-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TADA2L antibody (ABIN2780370)

Thompson, Yang, Power, Hufschmid, Beveridge, Reid, Ng, Armson, Ryan: "Identification of zoonotic Giardia genotypes in marsupials in Australia." in: Experimental parasitology, Vol. 120, Issue 1, pp. 88-93, (2008) (PubMed).

Target Details for TADA2L

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Alternative Name: TADA2L

Background:

Background Information: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.

Gene Name: Transcriptional adaptor 2A

Alternative Symbols: ADA2, ADA2A, KL04P, hADA2, TADA2L

Protein Name: Transcriptional adapter 2-alpha

Molecular Weight: 51kDa

Gene ID: 6871

NCBI Accession: NP_001479

UniProt: O75478

Pathways: Chromatin Binding